Spontaneous food allergy in Was−/− mice occurs independent of FcεRImediated mast cell activation

WS Lexmond, JA Goettel, BF Sallis, K McCann… - Allergy, 2017 - Wiley Online Library
… −/− mice indicating that IgE/FcεRI-mediated signals … spontaneous food allergy in Was −/−
Fcer1a −/− mice have the potential to provide a better understanding of IgE/FcεRI-independent

Il-10 enhances ige-mediated mast cell responses and is essential for the development of experimental food allergy in il-10–deficient mice

SH Polukort, J Rovatti, L Carlson… - The Journal of …, 2016 - journals.aai.org
… IL-10 −/− mice have been associated with the spontaneous … Data are representative of two
independent experiments.*p < … enhance the effects of FcεRI-mediated signaling events by …

[HTML][HTML] IgE and IgG antibodies as regulators of mast cell and basophil functions in food allergy

C Kanagaratham, YS El Ansari, OL Lewis… - Frontiers in …, 2020 - frontiersin.org
allergen exposure to damaged skin in mice, as can occur in … and thereby prevent
FcϵRI-mediated mast cell activation. … that two independent strains of mice lacking mast cells, Kit W-…

[HTML][HTML] Novel approaches in the inhibition of IgE-induced mast cell reactivity in food allergy

C Tontini, S Bulfone-Paus - Frontiers in immunology, 2021 - frontiersin.org
… reduced allergen-specific responses in a peanut allergy mouse … actin fibers that inhibit
FcϵRI-mediated calcium flux and … disease-modifying allergen-independent therapies available in …

[HTML][HTML] Experimental models for studying food allergy

C Kanagaratham, BF Sallis, E Fiebiger - Cellular and molecular …, 2018 - Elsevier
… In mice, mucosal mast cells are commonly quantified by … under germ-free conditions
and is thus independent of the … that IgE/FcεRI-mediated dendritic cell activation is part of a …

New mechanistic advances in FcεRI-mast cell–mediated allergic signaling

Y Li, PSC Leung, ME Gershwin, J Song - Clinical Reviews in Allergy & …, 2022 - Springer
… the peanut allergen rather than the canonical allergen itself … inhibition of Fas/FasL-independent
apoptosis, and increased … expression in mouse bone marrow–derived mast cells (BMMCs…

Mucosal mast cells as key effector cells in food allergies

N Nakano, J Kitaura - Cells, 2022 - mdpi.com
… that causes IgE-independent mast cell activation. The receptor … growth factor for both mouse
and human mast cells. It has … high-affinity IgE receptor FcεRI-mediated signaling, resulting in …

Suppression of IgE-mediated anaphylaxis and food allergy with monovalent anti-FcεRIα mAbs

MV Khodoun, SC Morris, WH Shao, C Potter… - Journal of Allergy and …, 2021 - Elsevier
… , mice that have large numbers of activated hu mast cells. … ; an IgE-independent decrease
in mast cell responsiveness (… mechanisms involved in FcεRI-mediated mast cell activation and …

Mast cells are required for experimental oral allergen–induced diarrhea

EB Brandt, RT Strait, D Hershko… - The Journal of …, 2003 - Am Soc Clin Investig
… Furthermore, diarrhea was largely IgE/FcεRI mediated and, … WT BALB/c mice of mast cells
by repeated administration of … the histamine-independent development of allergic diarrhea and …

Mouse models for food allergies: where do we stand?

S Schülke, M Albrecht - Cells, 2019 - mdpi.com
… in mast cell activation and expansion [13]. In affected … the induction of anaphylactic reactions
in an IgE-independent way via … study spontaneous oral sensitization towards food allergens. …